Objective To examine whether there are changes in cognitive function before vs after infection-related hospitalizations among NH residents.ĭesign, Setting, and Participants This cohort study used data from the Minimum Data Set 3.0 linked to Medicare hospitalization data from 2011 to 2017 for US nursing home residents aged 65 years or older who had experienced an infection-related hospitalization and had at least 2 quarterly Minimum Data Set assessments before and 4 or more after the infection-related hospitalization. Cognitive impairment, which markedly affects quality of life and caregiving needs, has been associated with hospitalizations, but the association between infection-related hospitalizations and long-term cognitive function among NH residents is unknown. Importance Hospitalizations for infections among nursing home (NH) residents remain common despite national initiatives to reduce them. Shared Decision Making and Communication.
Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.ICD-10 codes identifying sepsis-related complications ICD-9 codes identifying sepsis-related complicationsĮTable 10. Mean CFS scores and severe impairment prevalence at transfer by subgroupsĮTable 9. Association between infection-related hospitalization and cognitive function over time, using placebo hospitalization datesĮTable 6. Association between infection-related hospitalization and cognitive function over time, using alternate samplesĮTable 5. Average and heterogenous effect of infection-related hospitalization on cognitive function by sex, age, infection-related condition and Alzheimer's disease and related dementia at the time of transferĮTable 4. Association between infection-related hospitalization and cognitive function over timeĮTable 3. Characteristics of those surviving at least one year after, and those dying within the first or three quarters of infection-related hospitalizationĮTable 2. Change in presence of delirium symptoms before and after infection-related hospitalizationĮTable 1. Change in cognitive function before and after infection-related hospitalization, stratified by age and infection-related condition at transfer (sepsis vs other)ĮFigure 5. Share of NH residents dying after the infection-related hospital transferĮFigure 4. Descriptive characteristics of the analytical sampleĮFigure 3. Distribution of infection-related hospital transfer datesĮFigure 2.